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July 2011

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NIEHS fellow receives Endocrine Society Presidential Poster Award

By Ian Thomas
July 2011

Javier Revollo, Ph.D.

Presidential Poster Award winner Revollo (Photo courtesy of Steve McCaw)

NIEHS visiting fellow Javier Revollo, Ph.D., received the Presidential Poster Award at ENDO Expo 2011: The 93d Annual Meeting of the Endocrine Society( Exit NIEHS. Revollo's poster depicted his most recent research on glucocorticoids, steroid hormones that manage a variety of physiological processes, most notably metabolism and immunity.

"This study was inspired by our need to better understand how glucocorticoids work," Revollo explained. "Initially, we hoped to simply define the role of Hes1 in glucocorticoid signaling, and I feel that we've certainly accomplished that and much more. Ultimately, we discovered that Hes1 is actually a major regulator of the signaling process."

Given the broad use of glucocorticoids in many of today's prescribed drugs, the possible applications of this particular study appear promising, an opinion shared by Revollo's postdoctoral advisor and the Chief of NIEHS' Laboratory of Signal Transduction, John Cidlowski, Ph.D.

"Through the course of his research, Javier has discovered a novel pathway that could eventually lead to new approaches in treating inflammatory disease in men," Cidlowski noted.

Hailing originally from La Paz, Bolivia, Revollo recalls how his interest in science began at an early age through a childhood fascination with the many exotic insects of the region. That interest later took him to the University of Wisconsin, where he studied genetics before eventually moving on to Washington University, St. Louis where he earned his Ph.D. in molecular cell biology while working extensively on the biochemistry of aging. Now, having settled comfortably into life as a resident of Research Triangle Park, Revollo says he enjoys his work with the Institute, as well as collaborations with his fellow scientists and peers, many of whom he credits for much of his success.

"It's always exciting to have one's hard work recognized, but I couldn't have accomplished this honor without the unwavering support of my mentor, Dr. Cidlowski, my fellow lab colleagues, and many other wonderful individuals here at NIEHS," Revollo said. "This award represents team effort and collaboration, and I am very grateful to everyone for that input."

Founded in 1916, The Endocrine Society ( Exit NIEHS is the world's oldest, largest, and most active international organization devoted to research on hormones and the clinical practice of endocrinology. This year's meeting was held in Boston, Mass. and attracted more than 7,800 scientific attendees and 2,600 abstract presentations from around the world.

(Ian Thomas is a writer/editor in the NIEHS Office of Communications and Public Liaison)

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