Environmental Factor, January 2009, National Institute of Environmental Health Sciences
Upcoming Distinguished Lecturer Harinder Singh
By Eddy Ball
NIEHS will welcome the next speaker in its 2008-2009 Distinguished Lecture Series on June 9 at 11:00 in Rodbell Auditorium. Harinder Singh, Ph.D., will discuss "Gene Regulatory Networks Orchestrating Innate and Adaptive Immune Cell Fates" in a lecture hosted by Principal Investigator Paul Wade, Ph.D. of the NIEHS Eukaryotic Transcriptional Regulation Group.
Singh is the Louis Block Professor in the Department of Molecular Genetics and Cell Biology and a Howard Hughes Medical Institute (HHMI) investigator at the University of Chicago. His research interests include studying the molecules that control the development of different immune cells during hematopoiesis - the formation and development of blood cells - to better understand the networks of interconnected transcription factors, signaling molecules and miRNAs that regulate cell fate choice and developmental transitions.
Recent work in Singh's lab has focused on the ways that gene positioning in the nucleus affects gene expression. According to Singh, a more complete characterization of the molecular mechanism that cells use to position genes could one day help scientists develop interventions to take advantage of this process to manipulate the expression of genes involved in immune system diseases and even cancer.